16.07.2023 |
Jin-Jin Yang,Lei Lei,Di Qiu,Sai Chen1 Department of Anesthesiology, Pain and Perioperative Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People’s Republic of China
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,Li-Ka Xing,Jing-Wei Zhao
Postoperative delirium is common in older adult patients and associated with a poor prognosis.
The use of benzodiazepine was identified as an independent risk factor for delirium, but there is no randomized controlled trial regarding the relationship between remimazolam, a new ultra-short acting benzodiazepine, and postoperative delirium.
We designed a randomized controlled trial to evaluate if remimazolam increases the incidence of postoperative delirium compared with propofol in older adult patients undergoing orthopedic surgery with general anesthesia.
Received 08 Oct 2022, Accepted 11 Jan 2023, Published online: 20 Jan 2023