Predicting Functional Recovery and Quality of Life in Older Patients Undergoing Colorectal Cancer Surgery: Real-World Data From the International GOSAFE Study
PURPOSE
The GOSAFE study evaluates risk factors for failing to achieve good quality of life (QoL) and functional recovery (FR) in older patients undergoing surgery for colon and rectal cancer.
METHODS
Patients age 70 years and older undergoing major elective colorectal surgery were prospectively enrolled. Frailty assessment was performed and outcomes, including QoL (EQ-5D-3L) recorded (3/6 months postoperatively). Postoperative FR was defined as a combination of Activity of Daily Living ≥5 + Timed Up & Go test <20 seconds + MiniCog >2.
Authors: Montroni, Isacco; Ugolini, Giampaolo; Saur, Nicole M.; Rostoft, Siri; Spinelli, Antonino; Van Leeuwen, Barbara L.; De Liguori Carino, Nicola; Ghignone, Federico; Jaklitsch, Michael T.; Kenig, Jakub; Garutti, Anna; Zingaretti, Chiara; Foca, Flavia; Vertogen, Bernadette; Nanni, Oriana; Wexner, Steven D.; Audisio, Riccardo A.; Taffurelli, Giovanni; Zattoni, Davide; Tramelli, Paola; Sermonesi, Giacomo; Ercolani, Giorgio; Tauceri, Francesca; Perenze, Barbara; Di Pietrantonio, Daniela; Mirarchi, Mariateresa; Garulli, Gianluca; Alagna, Vincenzo; Lucchi, Andrea; Pirrera, Basilio; Monari, Francesco; Conti, Luigi; Capelli, Patrizio; Romboli, Andrea; Palmieri, Gerardo; Banchini, Filippo; Di Candido, Francesca; Carvello, Michele; Sacchi, Matteo; De Lucia, Francesca; Foppa, Caterina; Marano, Luigi; Spaziani, Alessandro; Castagnoli, Giampaolo; Bartoli, Alberto; Frain, Laura; Fox, Sam W.; Cardin, Kristin; De Leon, Luis E.; Trompetto, Mario; Gallo, Gaetano; Realis Luc, Alberto; Clerico, Giuseppe; Sammarco, Giuseppe; De Luca, Raffaele; Simone, Michele; Albano, Anna; Fejka, Michael; Bleier, Joshua IS; Plas, Matthijs; van der Wal-Huisman, Hanneke; Costanzi, Andrea; Mari, Giulio; Maggioni, Dario; Pellegrino, Roberta; Riggio, Valentina; Kenig, Jakub; Szabat, Kinga; Scabini, Stefano; Pertile, Davide; Epis, Lorenzo; Massobrio, Andrea; Soriero, Domenico; Nesbakken, Arild; Flåten Backe, Ingeborg; Lønn, Mariann; Ferrari, Giovanni; Mazzola, Michele; Magistro, Carmelo; Achilli, Pietro; Giani, Alessandro; Ioannidis, Orestis; Loutzidou, Lydia; Galanos-Demiris, Konstantinos; Pellino, Gianluca; Balducci, Genoveffa; Frezza, Barbara; Lucarini, Alessio; Santos, Claudia; Cooper, Lisa; Siam, Baha; Levy, Yochai; Brenner, Baruch; Kashtan, Hanoch; Belgrano, Valerio; Decian, Franco; Palermo, Beatrice; Eggenhöffner, Roberto; Albertelli, Manuela; Sánchez-Guillén, Luis; Arroyo, Antonio; López-Rodríguez, Francisco; Lario, Sandra; Lillo, Cristina; Baltatzis, Minas; Chan, Anthony K.C.; Siriwardena, Ajith K.; Da Silva, Giovanna
DOI: https://doi.org/10.1200/JCO.22.02195
Journal of Clinical Oncology, Volume 41, Number 34, 1 December 2023, pp. 5247-5262(16)
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