Objective: Older patients with cancer value functional outcomes as much as survival, but surgical studies lack functional recovery (FR) data. The value of a standardized frailty assessment has been confirmed, yet it's infrequently utilized due to time restrictions into everyday practice. The multicenter GOSAFE study was designed to (1) evaluate the trajectory of patients' quality of life (QoL) after cancer surgery (2) assess baseline frailty indicators in unselected patients (3) clarify the most relevant tools in predicting FR and clinical outcomes. This is a report of the study design and baseline patient evaluations.

Materials & Methods: GOSAFE prospectively collected a baseline multidimensional evaluation before major elective surgery in patients (≥70 years) from 26 international units. Short−/mid−/long-term surgical outcomes were recorded with QoL and FR data.

Authors: Isacco Montroni a, Siri Rostoft b, Antonino Spinelli c, Barbara L. Van Leeuwen d, Giorgio Ercolani e, Nicole M. Saur f, Michael T. Jaklitsch g, Ponnandai S. Somasundar h, Nicola de Liguori Carino i, Federico Ghignone a, Flavia Foca j, Chiara Zingaretti j, Riccardo A. Audisio k, Giampaolo Ugolini a

Journal of Geriatric Oncology, Volume 11, Issue 2, March 2020, Pages 244-255
https://doi.org/10.1016/j.jgo.2019.06.017

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