Accurate quality of life (QoL) data and functional results after cancer surgery are lacking for older patients.

Background

Accurate quality of life (QoL) data and functional results after cancer surgery are lacking for older patients. The international, multicenter Geriatric Oncology Surgical Assessment and Functional rEcovery after Surgery (GOSAFE) Study compares QoL before and after surgery and identifies predictors of decline in QoL.

Methods

GOSAFE prospectively collected data before and after major elective cancer surgery on older adults (≥70 years). Frailty assessment was performed and postoperative outcomes recorded (30, 90, and 180 days postoperatively) together with QoL data by means of the three-level version of the EuroQol five-dimensional questionnaire (EQ-5D-3L), including 2 components: an index (range = 0-1) generated by 5 domains (mobility, self-care, ability to perform the usual activities, pain or discomfort, anxiety or depression) and a visual analog scale.

Isacco Montroni, MD , Giampaolo Ugolini, MD , Nicole M Saur, MD , Siri Rostoft, MD , Antonino Spinelli, MD , Barbara L Van Leeuwen, MD , Nicola De Liguori Carino, MD , Federico Ghignone, MD , Michael T Jaklitsch, MD , Ponnandai Somasundar, MD , Anna Garutti, MD , Chiara Zingaretti, PhD , Flavia Foca, BSc , Bernadette Vertogen, BSc , Oriana Nanni, MStat , Steven D Wexner, MD , Riccardo A Audisio, MD 

JNCI: Journal of the National Cancer Institute, Volume 114, Issue 7, July 2022, Pages 969–978, https://doi.org/10.1093/jnci/djac071

 

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